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REACH Services Offered by VUOS

 

Are you a manufacturer or importer of chemicals and preparations made of them? If SO, you must cope with the new European legislation known under the acronym REACH, which entered into force on 1st June 2007 (Regulation No. 1907/2006 of the European Parliament and of the Council).

VUOS is able to significantly help you with this problem. We are the only facility in the Czech Republic and one of a few facilities in the EU, which is able to completely solve problems with the registration of products of chemical nature and further problems related to the requirements of REACH.

Complete Offer of Services by VUOS - REACH

The VUOS staff is ready to render broad assistance to our clients in:

  • assessment of impacts of the Regulation on the company, including an estimate of costs
  • search and usability evaluation of the literature information about substances
  • planning of necessary tests, incl. economic data
  • determination of the substance properties using the calculation method (Q)SAR
  • determination of the substance properties using the Read Across method, where possible
  • conducting tests, writing reports
  • elaboration of a plan of further testing for the European Chemicals Agency (ECHA)
  • elaboration of a registration dossier
  • elaboration of Chemical Safety Reports and Safety Data Sheets

VUOS holds all the necessary documents, certificates and authorizations for the mentioned activities, in particular:

Certificates on Good Laboratory Practice compliance
Authorization to work with laboratory animals

All the activities are carried out by highly qualified workers who rank among the absolute top in the Czech Republic in testing, assessment and elaboration of the respective documents. Therefore a number of them represent the country in the most important international professional bodies.

VUOS through its activities ensures performance of the base set of tests required for the registration of chemicals with an annual output exceeding 10 tonnes and elaboration of a proposal for further testing as required by the registration duties. On top of that, VUOS conducts, to a limited extent, also determination of chronic properties, such as chronic toxicity and carcinogenicity. These tests are not listed (due to their uniqueness) in the following overview, which contains also information on the methods used:

Overview of Tests Performed as Standard by VUOS in GLP Mode:

TEST

METODA

Melting point / Melting range

EU A.1 / OECD 102

Boiling point

EU A.2 / OECD 103

Relative density

EU A.3 / OECD 109

Vapour pressure (static method)

EU A.4 / OECD 104

Surface tension (aqueous solutions)

EU A.5 / OECD 115

Water solubility
- Column elution method
- Flask method

EU A.6 / OECD 105

Partition coefficient (n-octanol/water)
- Shake flask method
- HPLC method

EU A.8 / OECD 107
EU A.8 / OECD 117

Flash point (only at liquids)

EU A.9

Flammability (only at solids)

EU A.10

Flammability (contact with water)

EU A.12

Pyrophoric properties of solids and liquids

EU A.13

Explosive properties

EU A.14

Relative self-ignition temperature for solids

EU A.16

Oxidizing properties (solids)

EU A.17

Particle size distribution

ISO 13320-1

Acute toxicity oral - Acute toxic class method

EU B.1tris / OECD 423

Acute toxicity (dermal)

EU B.3 / OECD 402

Acute toxicity: Dermal irritation/corrosion

EU B.4 / OECD 404

Acute toxicity: Eye irritation/corrosion

EU B.5 / OECD 405

Skin sensitisation - Guinea-pig maximization test

EU B.6 / OECD 406

Skin sensitization - Local lymph node assay
(non-radioactive endpoint)

EU B.42 / OECD 429

Repeated dose oral toxicity (28-day toxicity study)

EU B.7 / OECD 407

Mutagenicity - In vivo Micronucleus test

EU B.12 / OECD 474

Mutagenicity - Reverse mutation test using bacteria

EU B.13/14 / OECD 471

Subchronic oral toxicity (90-day toxicity study)

EU B.26 / OECD 408

Teratogenicity test

EU B.31 / OECD 414

One-generation reproduction toxicity test

EU B.34 / OECD 415

Two-generation reproduction toxicity test

EU B.35 / OECD 416

Reproduction/Developmental Toxicity Screening Test

OECD 421

Combined Chronic Toxicity/Carcinogenicity Studies

EU B.33 / OECD 453

Acute toxicity for fish

EU C.1 / OECD 203

Acute toxicity for Daphnia

EU C.2 / OECD 202

Algal inhibition test

EU C.3 / OECD 201

Ready biodegradability
- DOC Test
- Modified OECD Screening Test
- Closed Bottle Test

EU C.4-A / OECD 301A
EU C.4-B / OECD 301E
EU C.4-E / OECD 301D

Biodegradation: Zahn-Wellens test

EU C.9 / OECD 302B

Hydrolysis as a function pH

EU C.7 / OECD 111

Biodegradation: Activated Sludge Respiration Inhibition Test

EU C.11 / OECD 209

Estimation of the adsorption coefficient (KOC)
onsoil and on sewage sludge using HPLC

EU C.19 / OECD 121

Development of analytic method

Validation of analytic method
- HPLC method
- GC method
- Titration method
- Spectrophotometric method

Risk Assesment

EU



Other services offered by VUOS:

VUOS holds the accreditation to ISO EN 17025 (Testing Laboratory) and to ISO EN 45011 (Certification Body), which enables us to carry out, among others, analyses of virtually all types of chemicals in virtually all types of matrices. Thus we are able to perform the mentioned jobs both for the needs of individual companies and for the purpose of reporting to the state administration bodies. This concerns the following areas:

  • Analytics of the environment
  • Development of analytical methods
  • Certification of product compliance with standards
  • Registration of cosmetic products

In addition to this, VUOS deals with orders related to environmental damages, including old burdens; these activities are performed in cooperation with the leading Czech remediation companies.