REACH Services Offered by VUOS

Are you a manufacturer or importer of chemicals and preparations made of them? If SO, you must cope with the new European legislation known under the acronym REACH, which entered into force on 1st June 2007 (Regulation No. 1907/2006 of the European Parliament and of the Council).

VUOS is able to significantly help you with this problem. We are the only facility in the Czech Republic and one of a few facilities in the EU, which is able to completely solve problems with the registration of products of chemical nature and further problems related to the requirements of REACH.

Complete Offer of Services by VUOS - REACH

The VUOS staff is ready to render broad assistance to our clients in:

assessment of impacts of the Regulation on the company, including an estimate of costs
search and usability evaluation of the literature information about substances
planning of necessary tests, incl. economic data
determination of the substance properties using the calculation method (Q)SAR
determination of the substance properties using the Read Across method, where possible
conducting tests, writing reports
elaboration of a plan of further testing for the European Chemicals Agency (ECHA)
elaboration of a registration dossier
elaboration of Chemical Safety Reports and Safety Data Sheets

VUOS holds all the necessary documents, certificates and authorizations for the mentioned activities, in particular:

Certificates on Good Laboratory Practice compliance
Authorization to work with laboratory animals

All the activities are carried out by highly qualified workers who rank among the absolute top in the Czech Republic in testing, assessment and elaboration of the respective documents. Therefore a number of them represent the country in the most important international professional bodies.

VUOS through its activities ensures performance of the base set of tests required for the registration of chemicals with an annual output exceeding 10 tonnes and elaboration of a proposal for further testing as required by the registration duties. On top of that, VUOS conducts, to a limited extent, also determination of chronic properties, such as chronic toxicity and carcinogenicity. These tests are not listed (due to their uniqueness) in the following overview, which contains also information on the methods used:

Overview of Tests Performed as Standard by VUOS in GLP Mode:

TEST	METODA
Melting point / Melting range	EU A.1 / OECD 102
Boiling point	EU A.2 / OECD 103
Relative density	EU A.3 / OECD 109
Vapour pressure (static method)	EU A.4 / OECD 104
Surface tension (aqueous solutions)	EU A.5 / OECD 115
Water solubility - Column elution method - Flask method	EU A.6 / OECD 105
Partition coefficient (n-octanol/water) - Shake flask method - HPLC method	EU A.8 / OECD 107 EU A.8 / OECD 117
Flash point (only at liquids)	EU A.9
Flammability (only at solids)	EU A.10
Flammability (contact with water)	EU A.12
Pyrophoric properties of solids and liquids	EU A.13
Explosive properties	EU A.14
Relative self-ignition temperature for solids	EU A.16
Oxidizing properties (solids)	EU A.17
Particle size distribution	ISO 13320-1
Acute toxicity oral - Acute toxic class method	EU B.1tris / OECD 423
Acute toxicity (dermal)	EU B.3 / OECD 402
Acute toxicity: Dermal irritation/corrosion	EU B.4 / OECD 404
Acute toxicity: Eye irritation/corrosion	EU B.5 / OECD 405
Skin sensitisation - Guinea-pig maximization test	EU B.6 / OECD 406
Skin sensitization - Local lymph node assay (non-radioactive endpoint)	EU B.42 / OECD 429
Repeated dose oral toxicity (28-day toxicity study)	EU B.7 / OECD 407
Mutagenicity - In vivo Micronucleus test	EU B.12 / OECD 474
Mutagenicity - Reverse mutation test using bacteria	EU B.13/14 / OECD 471
Subchronic oral toxicity (90-day toxicity study)	EU B.26 / OECD 408
Teratogenicity test	EU B.31 / OECD 414
One-generation reproduction toxicity test	EU B.34 / OECD 415
Two-generation reproduction toxicity test	EU B.35 / OECD 416
Reproduction/Developmental Toxicity Screening Test	OECD 421
Combined Chronic Toxicity/Carcinogenicity Studies	EU B.33 / OECD 453
Acute toxicity for fish	EU C.1 / OECD 203
Acute toxicity for Daphnia	EU C.2 / OECD 202
Algal inhibition test	EU C.3 / OECD 201
Ready biodegradability - DOC Test - Modified OECD Screening Test - Closed Bottle Test	EU C.4-A / OECD 301A EU C.4-B / OECD 301E EU C.4-E / OECD 301D
Biodegradation: Zahn-Wellens test	EU C.9 / OECD 302B
Hydrolysis as a function pH	EU C.7 / OECD 111
Biodegradation: Activated Sludge Respiration Inhibition Test	EU C.11 / OECD 209
Estimation of the adsorption coefficient (KOC) onsoil and on sewage sludge using HPLC	EU C.19 / OECD 121
Development of analytic method
Validation of analytic method - HPLC method - GC method - Titration method - Spectrophotometric method
Risk Assesment	EU

Other services offered by VUOS:

VUOS holds the accreditation to ISO EN 17025 (Testing Laboratory) and to ISO EN 45011 (Certification Body), which enables us to carry out, among others, analyses of virtually all types of chemicals in virtually all types of matrices. Thus we are able to perform the mentioned jobs both for the needs of individual companies and for the purpose of reporting to the state administration bodies. This concerns the following areas:

Analytics of the environment
Development of analytical methods
Certification of product compliance with standards
Registration of cosmetic products

In addition to this, VUOS deals with orders related to environmental damages, including old burdens; these activities are performed in cooperation with the leading Czech remediation companies.