List of Methods

 

TEST

METODA

Melting point / Melting range

EU A.1 / OECD 102

Boiling point

EU A.2 / OECD 103

Relative density

EU A.3 / OECD 109

Vapour pressure (static method)

EU A.4 / OECD 104

Surface tension (aqueous solutions)

EU A.5 / OECD 115

Water solubility
- Column elution method
- Flask method

EU A.6 / OECD 105

Partition coefficient (n-octanol/water)
- Shake flask method
- HPLC method

EU A.8 / OECD 107
EU A.8 / OECD 117

Flash point (only at liquids)

EU A.9

Flammability (only at solids)

EU A.10

Flammability (contact with water)

EU A.12

Pyrophoric properties of solids and liquids

EU A.13

Explosive properties

EU A.14

Relative self-ignition temperature for solids

EU A.16

Oxidizing properties (solids)

EU A.17

Particle size distribution

ISO 13320-1

Acute toxicity oral - Acute toxic class method

EU B.1tris / OECD 423

Acute toxicity (dermal)

EU B.3 / OECD 402

Acute toxicity: Dermal irritation/corrosion

EU B.4 / OECD 404

Acute toxicity: Eye irritation/corrosion

EU B.5 / OECD 405

Skin sensitisation - Guinea-pig maximization test

EU B.6 / OECD 406

Skin sensitization - Local lymph node assay
(non-radioactive endpoint)

EU B.42 / OECD 429

Repeated dose oral toxicity (28-day toxicity study)

EU B.7 / OECD 407

Mutagenicity - In vivo Micronucleus test

EU B.12 / OECD 474

Mutagenicity - Reverse mutation test using bacteria

EU B.13/14 / OECD 471

Subchronic oral toxicity (90-day toxicity study)

EU B.26 / OECD 408

Teratogenicity test

EU B.31 / OECD 414

One-generation reproduction toxicity test

EU B.34 / OECD 415

Two-generation reproduction toxicity test

EU B.35 / OECD 416

Reproduction/Developmental Toxicity Screening Test

OECD 421

Combined Chronic Toxicity/Carcinogenicity Studies

EU B.33 / OECD 453

Acute toxicity for fish

EU C.1 / OECD 203

Acute toxicity for Daphnia

EU C.2 / OECD 202

Algal inhibition test

EU C.3 / OECD 201

Ready biodegradability
- DOC Test
- Modified OECD Screening Test
- Closed Bottle Test

EU C.4-A / OECD 301A
EU C.4-B / OECD 301E
EU C.4-E / OECD 301D

Biodegradation: Zahn-Wellens test

EU C.9 / OECD 302B

Hydrolysis as a function pH

EU C.7 / OECD 111

Biodegradation: Activated Sludge Respiration Inhibition Test

EU C.11 / OECD 209

Estimation of the adsorption coefficient (KOC)
onsoil and on sewage sludge using HPLC

EU C.19 / OECD 121

Development of analytic method

Validation of analytic method
- HPLC method
- GC method
- Titration method
- Spectrophotometric method

Risk Assesment

EU